Cleveland Clinic gets $3.8M grant to study heart failure

Cleveland Clinic has received a $3.8 million federal grant to study the cellular processes that lead to heart failure.

The project’s goal is to determine why some patients are at risk of developing heart failure and others are not, while also identifying targets for future treatment options, according to a statement from the Clinic. The project has been labeled Cleveland Heart and Metabolic Prevention Study, or CHAMPS.

“Say two people have heart attacks; in one, the heart function is relatively preserved, while in the other, the heart function deteriorates,” said Dr. Jerry Tang, the study’s principal investigator. “With this study, we hope to discover why, so that we can personalize therapy and treat each patient accordingly.”

The researchers hope to identify heart failure causes by focusing on metabolic pathways associated with nitric oxide, which has been linked to the development of heart disorders.